Burkholderia cenocepacia J2315, BCAL3118 (wecA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3118
NCBI Locus TagQU43_RS52320
Name
wecA
Replicon chromosome 1
Genomic location 3407941 - 3409047 (+ strand)
CommentBelongs to the O antigen biosynthesis gene cluster

Cross-References

RefSeq WP_006485106.1
GI 206561464
Entrez 6933617
GI 206561464
INSDC CAR53442.1
NCBI Locus Tag QU43_RS52320
NCBI Old Locus Tag BCAL3118
RefSeq WP_006485106.1,GeneID
UniParc UPI00017B9955
UniProtKB Acc B4ECD9
UniProtKB ID B4ECD9_BURCJ
UniRef100 UniRef100_B4ECD9
UniRef50 UniRef50_L9PGE7
UniRef90 UniRef90_A9AF84

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylglucosamine-1-P transferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 20.74
Kyte-Doolittle Hydrophobicity Value 0.869
Molecular Weight (kDa) 41015.9
Isoelectric Point (pI) 10.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 412 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000744 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3118
Search term: wecA

References

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA.
J Bacteriol. 2005 Feb;187(4):1324-33.
PubMed ID: 15687196