Burkholderia cenocepacia J2315, BCAL1929 (arnT)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
NCBI Locus TagQU43_RS46190
Replicon chromosome 1
Genomic location 2128443 - 2130119 (+ strand)
CommentIn PMID:27597847: arnT, arnB, arnC, arnA1, arnA2, and BCAL1935 located in the arn gene cluster harbored significantly low frequencies of transposon insertions (TraDIS). They were therefore categorized as essential by the authors.


RefSeq WP_006482861.1
GI 206560293
Entrez 6932119
GI 206560293
INSDC CAR52230.1
NCBI Locus Tag QU43_RS46190
NCBI Old Locus Tag BCAL1929
RefSeq WP_006482861.1,GeneID
UniParc UPI00017B921E
UniProtKB Acc B4EB15
UniRef100 UniRef100_A0A0D1BVQ3
UniRef50 UniRef50_E5AQP3
UniRef90 UniRef90_A9AG56


Feature Type CDS
Coding Frame 1
Product Name
4-amino-4-deoxy-L-arabinose transferase ArnT
Product Name Confidence: Class 1
Synonyms aminoarabinose transferase
putative undecaprenyl phosphate-alpha-4-amino-4-deoxy-l-arabinose arabinosy transferase
Evidence for Translation
Charge (pH 7) 18.09
Kyte-Doolittle Hydrophobicity Value 0.493
Molecular Weight (kDa) 62686.3
Isoelectric Point (pI) 10.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 1
direct assay evidence used in manual assertion
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 249 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001691 (653 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1929
Search term: arnT


A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.
Ortega XP, Cardona ST, Brown AR, Loutet SA, Flannagan RS, Campopiano DJ, Govan JR, Valvano MA.
J Bacteriol. 2007 May;189(9):3639-44.
PubMed ID: 17337576
PubMed ID: 22742453
PubMed ID: 26515403
PubMed ID: 26030265
An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor.
Trent MS, Ribeiro AA, Lin S, Cotter RJ, Raetz CR.
J Biol Chem. 2001 Nov 16;276(46):43122-3Epub 2001 Sep 4.
PubMed ID: 11535604
PubMed ID: 27597847