Burkholderia cenocepacia J2315, BCAL0967 (waaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL0967
NCBI Locus TagQU43_RS41385
Name
waaF
Replicon chromosome 1
Genomic location 1055349 - 1056386 (- strand)

Cross-References

RefSeq WP_006482498.1
GI 206559360
Entrez 6931359
GI 206559360
INSDC CAR51274.1
NCBI Locus Tag QU43_RS41385
NCBI Old Locus Tag BCAL0967
RefSeq WP_006482498.1,GeneID
UniParc UPI00017B8F8C
UniProtKB Acc B4EBZ7
UniProtKB ID B4EBZ7_BURCJ
UniRef100 UniRef100_A0A095DQ11
UniRef50 UniRef50_Q1LR49
UniRef90 UniRef90_A0A095DQ11

Product

Feature Type CDS
Coding Frame 1
Product Name
heptosyltransferase II WaaF
Product Name Confidence: Class 1
Synonyms putative ADP-heptose--LPS heptosyltransferase II
Evidence for Translation
Charge (pH 7) 9.15
Kyte-Doolittle Hydrophobicity Value -0.087
Molecular Weight (kDa) 37827.4
Isoelectric Point (pI) 8.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 320 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002492 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0967
Search term: waaF

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldias MS, Bates CC, Molinaro A, Valvano MA.
J Biol Chem. 2009 Aug 7;284(32):21738-5Epub 2009 Jun 12.
PubMed ID: 19525227
Isolation of polymyxin B-susceptible mutants of Burkholderia pseudomallei and molecular characterization of genetic loci involved in polymyxin B resistance.
Burtnick MN, Woods DE.
Antimicrob Agents Chemother. 1999 Nov;43(11):2648-56.
PubMed ID: 10543742