Burkholderia mallei ATCC 23344, BMAA1528 (bprD)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
Locus Tag
Synonym: sctA
Replicon chromosome 2
Genomic location 1657230 - 1658087 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.


RefSeq YP_106118.1
GI 53716477
NCBI Locus Tag BMAA1528
RefSeq YP_106118.1,GeneID


Feature Type CDS
Coding Frame 1
Product Name
type III secretion system needle tip protein BipD (T3SS-3)
Product Name Confidence: Class 2
Synonyms BprD protein
Evidence for Translation
Charge (pH 7) -7.27
Kyte-Doolittle Hydrophobicity Value -0.387
Molecular Weight (kDa) 31165.8
Isoelectric Point (pI) 4.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2IXR TOXIN 07/10/06 BipD of Burkholderia Pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.6 X-RAY DIFFRACTION 100.0
3NFT TRANSPORT PROTEIN 06/10/10 Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 1.51 X-RAY DIFFRACTION 100.0
2IZP TOXIN 07/25/06 BipD - an invasion protein associated with the type-III secretion system of Burkholderia pseudomallei. BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 100.0
2J9T TOXIN 11/16/06 BipD of Burkholderia Pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019830 (320 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1528
Search term: bprD


Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268