Burkholderia thailandensis E264; ATCC 700388, BTH_I1470 (rmlA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264; ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_I1470
NCBI Locus TagBTH_RS19700
Name
rmlA
Synonym: rfbA
Replicon chromosome I
Genomic location 1665731 - 1666669 (+ strand)
Transposon Mutants 3 transposon mutants in E264; ATCC 700388
CommentBelongs to the Type II O-antigenic polysaccharide biosynthesis gene cluster

Cross-References

RefSeq YP_442016.1
GI 83718471
Entrez 3847006
GI 83718471
INSDC ABC36359.1
NCBI Locus Tag BTH_RS19700
NCBI Old Locus Tag BTH_I1470
RefSeq YP_442016.1
UniParc UPI0000667B99
UniProtKB Acc Q2SYI3
UniProtKB ID Q2SYI3_BURTA
UniRef100 UniRef100_Q2SYI3
UniRef50 UniRef50_P37744
UniRef90 UniRef90_Q9AEV6

Product

Feature Type CDS
Coding Frame 1
Product Name
glucose-1-phosphate thymidylyltransferase RmlA
Product Name Confidence: Class 1
Synonyms glucose-1-phosphate thymidylyltransferase
Evidence for Translation
Charge (pH 7) -0.86
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 34749.3
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 634 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000731 (658 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_I1470
Search term: rmlA

Human Homologs

Ensembl 86, assembly GRCh38.p7
eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]
E-value: 4.6e-06
Percent Identity: 37.5

References

PubMed ID: 21640586