Burkholderia thailandensis E264; ATCC 700388, BTH_II2099 (malM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264; ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II2099
NCBI Locus TagBTH_RS10740
Name
malM
Replicon chromosome II
Genomic location 2577785 - 2579653 (+ strand)
Transposon Mutants 2 transposon mutants in E264; ATCC 700388
CommentBelongs to the malleilactone biosynthetic gene cluster

Cross-References

RefSeq YP_440287.1
GI 83718033
Entrez 3844687
GI 83718033
NCBI Locus Tag BTH_RS10740
NCBI Old Locus Tag BTH_II2099
RefSeq WP_009894059.1
UniProtKB Acc Q2T3G2
UniProtKB ID Q2T3G2_BURTA

Product

Feature Type CDS
Coding Frame 1
Product Name
MalM
Synonyms AMP-binding domain-containing protein
Evidence for Translation
Charge (pH 7) -5.85
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 66879.0
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 539 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019792 (370 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II2099
Search term: malM
Search term: MalM

Human Homologs

Ensembl 86, assembly GRCh38.p7
acyl-CoA synthetase bubblegum family member 1 [Source:HGNC Symbol;Acc:HGNC:29567]
E-value: 1.9e-11
Percent Identity: 25.4

References

PubMed ID: 29087175
PubMed ID: 22765305