Burkholderia pseudomallei K96243, BPSS1992

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1992
Name
Replicon chromosome 2
Genomic location 2693248 - 2695182 (- strand)

Cross-References

RefSeq YP_111998.1
GI 53723013
Entrez 3096963
GI 53723013
INSDC CAH39470.1
NCBI Locus Tag BPSS1992
RefSeq YP_111998.1,GeneID
UniParc UPI000043BEE7
UniProtKB Acc Q63IS4
UniProtKB ID Q63IS4_BURPS
UniRef100 UniRef100_A0A069BI72
UniRef50 UniRef50_B4EHZ5
UniRef90 UniRef90_Q3JJJ5

Product

Feature Type CDS
Coding Frame 1
Product Name
x-prolyl-dipeptidyl aminopeptidase
Synonyms
Evidence for Translation
Charge (pH 7) -2.19
Kyte-Doolittle Hydrophobicity Value -0.176
Molecular Weight (kDa) 68190.9
Isoelectric Point (pI) 6.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 68 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004051 (593 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1992

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268