Burkholderia pseudomallei K96243, BPSS1553 (bprP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1553
Name
bprP
Replicon chromosome 2
Genomic location 2106912 - 2107883 (+ strand)
CommentThis gene is part of the type III secretion system T3SS-3 (bsa) gene locus.

Cross-References

RefSeq YP_111559.1
GI 53722574
Entrez 3095781
GI 53722574
INSDC CAH39026.1
NCBI Locus Tag BPSS1553
RefSeq YP_111559.1,GeneID
UniParc UPI000043BD33
UniProtKB Acc Q63K13
UniProtKB ID Q63K13_BURPS
UniRef100 UniRef100_A0A069BA09
UniRef50 UniRef50_D7SFB6
UniRef90 UniRef90_D7SFB6

Product

Feature Type CDS
Coding Frame 1
Product Name
regulator of type III secretion system-3 (T3SS-3) BprP
Product Name Confidence: Class 2
Synonyms hypothetical protein
BprP
Evidence for Translation
Charge (pH 7) 0.35
Kyte-Doolittle Hydrophobicity Value -0.155
Molecular Weight (kDa) 34714.9
Isoelectric Point (pI) 7.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019868 (325 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1553
Search term: bprP

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon.
Chen Y, Schröder I, French CT, Jaroszewicz A, Yee XJ, Teh BE, Toesca IJ, Miller JF, Gan YH
BMC Microbiol 2014 Aug 1;14:206
PubMed ID: 25085508
Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei.
Sun GW, Chen Y, Liu Y, Tan GY, Ong C, Tan P, Gan YH
Mol Microbiol 2010 May;76(3):677-89
PubMed ID: 20345664
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152