Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
|Genomic location||719014 - 720087 (+ strand)|
|Comment||Gene is part of a cluster known as the type VI secretion system gene cluster tss-6 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-3 cluster later (PMID:22007185)|
|Comment||Gene is part of a cluster known as the type VI secretion system gene cluster tss-4 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-2 cluster later (PMID:22007185)|
|NCBI Locus Tag||BPSS0526|
type VI secretion system protein TssM-6
type VI secretion system-associated protein TagB-4
|Evidence for Translation|
|Charge (pH 7)||-2.34|
|Kyte-Doolittle Hydrophobicity Value||-0.235|
|Molecular Weight (kDa)||39341.9|
|Isoelectric Point (pI)||6.51|
|Additional evidence for subcellular localization|
Found in both pathogen and nonpathogenic strainsHits to this gene were found in 77 genera
|Burkholderia Ortholog Group||
BG019189 (324 members)
|Putative Inparalogs||None Found|
|STRING database||Search for predicted protein-protein interactions using:
Search term: BPSS0526
Search term: tssM-6
Search term: type VI secretion system protein TssM-6
In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.Shalom G, Shaw JG, Thomas MS.
Microbiology. 2007 Aug;153(Pt 8):2689-99.
PubMed ID: 17660433
PubMed ID: 22007185
Type VI secretion is a major virulence determinant in Burkholderia mallei.Schell MA(1), Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, MrÃ¡zek J, Nierman WC, Deshazer D.
Mol Microbiol. 2007 Jun;64(6):1466-85.
PubMed ID: 17555434