Burkholderia pseudomallei K96243, BPSS0482 (hhqB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0482
Name
hhqB
Replicon chromosome 2
Genomic location 654607 - 655497 (+ strand)

Cross-References

RefSeq YP_110504.1
GI 53721519
Entrez 3096432
GI 53721519
INSDC CAH37938.1
NCBI Locus Tag BPSS0482
RefSeq YP_110504.1,GeneID
UniParc UPI000043B92E
UniProtKB Acc Q63N15
UniProtKB ID Q63N15_BURPS
UniRef100 UniRef100_A0A095STK4
UniRef50 UniRef50_B1Z5C1
UniRef90 UniRef90_Q3JGW8

Product

Feature Type CDS
Coding Frame 1
Product Name
HhqB
Synonyms
Evidence for Translation
Charge (pH 7) -2.65
Kyte-Doolittle Hydrophobicity Value 0.140
Molecular Weight (kDa) 30557.3
Isoelectric Point (pI) 6.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 39 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017404 (462 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0482
Search term: hhqB
Search term: HhqB

Human Homologs

References

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria.
Diggle SP, Lumjiaktase P, Dipilato F, Winzer K, Kunakorn M, Barrett DA, Chhabra SR, Cámara M, Williams P
Chem Biol 2006 Jul;13(7):701-10
PubMed ID: 16873018