Burkholderia pseudomallei K96243, BPSL2300 (pdhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2300
Name
pdhB
Replicon chromosome 1
Genomic location 2768796 - 2770436 (- strand)

Cross-References

RefSeq YP_108896.1
GI 53719910
Entrez 3092156
GI 53719910
INSDC CAH36303.1
NCBI Locus Tag BPSL2300
RefSeq YP_108896.1,GeneID
UniParc UPI000043B31F
UniProtKB Acc Q63SM0
UniProtKB ID Q63SM0_BURPS
UniRef100 UniRef100_Q63SM0
UniRef50 UniRef50_A0A075P1Q2
UniRef90 UniRef90_A9AGT3

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -2.33
Kyte-Doolittle Hydrophobicity Value 0.036
Molecular Weight (kDa) 56295.0
Isoelectric Point (pI) 6.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 525 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002029 (629 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2300
Search term: pdhB

Human Homologs

Ensembl 97, assembly GRCh38.p12
pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]
E-value: 1.2e-31
Percent Identity: 30.5

Human Homologs

Ensembl 97, assembly GRCh38.p12
pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]
E-value: 1.2e-31
Percent Identity: 30.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268