Burkholderia pseudomallei K96243, BPSL2250 (suhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2250
Name
suhB
Replicon chromosome 1
Genomic location 2712459 - 2713262 (+ strand)

Cross-References

RefSeq YP_108845.1
GI 53719859
Entrez 3092894
GI 53719859
INSDC CAH36252.1
NCBI Locus Tag BPSL2250
RefSeq YP_108845.1,GeneID
UniParc UPI000043B2EC
UniProtKB Acc Q63SS1
UniProtKB ID Q63SS1_BURPS
UniRef100 UniRef100_Q3JQS8
UniRef50 UniRef50_Q3JQS8
UniRef90 UniRef90_Q3JQS8

Product

Feature Type CDS
Coding Frame 1
Product Name
inositol monophosphatase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (32.2 kDa, pI 4.95, PMID:21960737)
Charge (pH 7) -4.38
Kyte-Doolittle Hydrophobicity Value -0.193
Molecular Weight (kDa) 29333.8
Isoelectric Point (pI) 5.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 566 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001977 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2250
Search term: suhB

Human Homologs

Ensembl 97, assembly GRCh38.p12
inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050]
E-value: 1.6e-37
Percent Identity: 33.7

Human Homologs

Ensembl 97, assembly GRCh38.p12
inositol monophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:6050]
E-value: 1.6e-37
Percent Identity: 33.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268