Burkholderia pseudomallei K96243, BPSL0893 (fusA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0893
Name
fusA
Replicon chromosome 1
Genomic location 1039748 - 1041862 (- strand)

Cross-References

RefSeq YP_107519.1
GI 53718533
Entrez 3092467
GI 53718533
INSDC CAH34886.1
NCBI Locus Tag BPSL0893
RefSeq YP_107519.1,GeneID
UniParc UPI000043ADC8
UniProtKB Acc Q63WJ7
UniProtKB ID EFG1_BURPS
UniRef100 UniRef100_Q62HK4
UniRef50 UniRef50_Q9SI75
UniRef90 UniRef90_Q1BU86

Product

Feature Type CDS
Coding Frame 1
Product Name
elongation factor G
Synonyms
Evidence for Translation
Charge (pH 7) -20.17
Kyte-Doolittle Hydrophobicity Value -0.334
Molecular Weight (kDa) 77807.1
Isoelectric Point (pI) 5.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000255 (1306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0893
Search term: fusA

Human Homologs

Ensembl 97, assembly GRCh38.p12
G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780]
E-value: 2.3e-152
Percent Identity: 44.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268