Burkholderia pseudomallei K96243, BPSL0893 (fusA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0893
Name
fusA
Replicon chromosome 1
Genomic location 1039748 - 1041862 (- strand)

Cross-References

RefSeq YP_107519.1
GI 53718533
Entrez 3092467
GI 53718533
INSDC CAH34886.1
NCBI Locus Tag BPSL0893
RefSeq YP_107519.1,GeneID
UniParc UPI000043ADC8
UniProtKB Acc Q63WJ7
UniProtKB ID EFG1_BURPS
UniRef100 UniRef100_Q62HK4
UniRef50 UniRef50_Q9SI75
UniRef90 UniRef90_Q1BU86

Product

Feature Type CDS
Coding Frame 1
Product Name
elongation factor G
Synonyms
Evidence for Translation
Charge (pH 7) -20.17
Kyte-Doolittle Hydrophobicity Value -0.334
Molecular Weight (kDa) 77807.1
Isoelectric Point (pI) 5.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000255 (1306 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0893
Search term: fusA

Human Homologs

Ensembl 97, assembly GRCh38.p12
G elongation factor mitochondrial 1 [Source:HGNC Symbol;Acc:HGNC:13780]
E-value: 2.3e-152
Percent Identity: 44.2

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268