Burkholderia pseudomallei K96243, BPSL0547 (ssb)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0547
Name
ssb
Replicon chromosome 1
Genomic location 601561 - 602115 (+ strand)

Cross-References

RefSeq YP_107172.1
GI 53718186
Entrez 3094097
GI 53718186
INSDC CAH34536.1
NCBI Locus Tag BPSL0547
RefSeq YP_107172.1,GeneID
UniParc UPI000043AC6F
UniProtKB Acc Q63XJ3
UniProtKB ID Q63XJ3_BURPS
UniRef100 UniRef100_A0A097Y1U2
UniRef50 UniRef50_P59928
UniRef90 UniRef90_A1UZL0

Product

Feature Type CDS
Coding Frame 1
Product Name
single-stranded DNA-binding protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (20.1 kDa, pI 5.68, PMID:21960737)
Charge (pH 7) -1.77
Kyte-Doolittle Hydrophobicity Value -0.630
Molecular Weight (kDa) 18719.4
Isoelectric Point (pI) 5.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002628 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0547
Search term: ssb

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

Human Homologs

Ensembl 97, assembly GRCh38.p12
single stranded DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11317]
E-value: 5.2e-11
Percent Identity: 32.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268