Burkholderia pseudomallei K96243, BPSL0298 (argG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0298
Name
argG
Replicon chromosome 1
Genomic location 314669 - 316009 (+ strand)

Cross-References

RefSeq YP_106925.1
GI 53717939
Entrez 3091609
GI 53717939
INSDC CAH34287.1
NCBI Locus Tag BPSL0298
RefSeq YP_106925.1,GeneID
UniParc UPI000043AB7A
UniProtKB Acc Q63Y90
UniProtKB ID Q63Y90_BURPS
UniRef100 UniRef100_A3MNB7
UniRef50 UniRef50_Q8Z3H5
UniRef90 UniRef90_A3MNB7

Product

Feature Type CDS
Coding Frame 1
Product Name
argininosuccinate synthase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (47.2 kDa, pI 5.26, PMID:21960737)
Charge (pH 7) -7.84
Kyte-Doolittle Hydrophobicity Value -0.352
Molecular Weight (kDa) 49696.9
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004777 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0298
Search term: argG

Human Homologs

Ensembl 97, assembly GRCh38.p12
argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]
E-value: 1.0e-41
Percent Identity: 29.4

Human Homologs

Ensembl 97, assembly GRCh38.p12
argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]
E-value: 1.0e-41
Percent Identity: 29.4

Human Homologs

Ensembl 97, assembly GRCh38.p12
argininosuccinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:758]
E-value: 1.0e-41
Percent Identity: 29.4

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268