Burkholderia cenocepacia H111, I35_RS01710 (tssJ)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
Locus Tag
NCBI Old Locus TagI35_0330%2CI35_0387
Synonym: bcsN
Replicon chromosome 1
Genomic location 350221 - 350832 (- strand)
CommentPart of the T6SS gene cluster


RefSeq WP_034178609.1
GI 736004691
NCBI Locus Tag I35_RS01710
NCBI Old Locus Tag I35_0330%2CI35_0387
RefSeq WP_034178609.1


Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssJ
Product Name Confidence: Class 2
Synonyms membrane protein
Evidence for Translation
Charge (pH 7) 4.10
Kyte-Doolittle Hydrophobicity Value 0.152
Molecular Weight (kDa) 21253.4
Isoelectric Point (pI) 8.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000364 (626 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS01710
Search term: tssJ


A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
Towards a structural comprehension of bacterial type VI secretion systems: characterization of the TssJ-TssM complex of an Escherichia coli pathovar.
Felisberto-Rodrigues C, Durand E, Aschtgen MS, Blangy S, Ortiz-Lombardia M, Douzi B, Cambillau C, Cascales E
PLoS Pathog 2011 Nov;7(11):e1002386
PubMed ID: 22102820
Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149