Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS20790 (bptpA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS20790
|
| NCBI Old Locus Tag | BURCENK562V_C0973 |
| Name |
bptpA
|
| Replicon | ctg7180000002937 |
| Genomic location | 136952 - 137434 (+ strand) |
Cross-References
| RefSeq | WP_006481978.1 |
| GI | 493527948 |
| GI | 493527948 |
| NCBI Locus Tag | BURCENK562V_RS20790 |
| NCBI Old Locus Tag | BURCENK562V_C0973 |
| RefSeq | WP_006481978.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Burkholderia phosphotyrosine phosphatase, BPtpA
|
| Synonyms |
Low molecular weight protein tyrosine phosphatase, class II.I |
| Evidence for Translation | |
| Charge (pH 7) | -2.44 |
| Kyte-Doolittle Hydrophobicity Value | -0.232 |
| Molecular Weight (kDa) | 17499.6 |
| Isoelectric Point (pI) | 5.73 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG002021 (651 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS20790
Search term: bptpA
Search term: Burkholderia phosphotyrosine phosphatase, BPtpA
|
Human Homologs
References
|
The BPtpA protein from Burkholderia cenocepacia belongs to a new subclass of low molecular weight protein tyrosine phosphatases.
Sánchez-Rodríguez R, González GM, Becerril-García MA, Treviño-Rangel RJ, Marcos-Vilchis A, González-Pedrajo B, Valvano MA, Andrade A
Arch Biochem Biophys 2020 Mar 15;681:108277
PubMed ID: 31978399
|