Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS34645 (ptwH)

Cytoplasmic Membrane
Outer Membrane

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
NCBI Old Locus TagBURCENK562V_C0077
Replicon ctg7180000002935
Genomic location 41556 - 42986 (- strand)
CommentThis gene is part of the B. cenocepacia K56-2 plasmid-encoded ptw type IV secretion cluster.


RefSeq WP_034178478.1
GI 736004560
GI 736004560
NCBI Locus Tag BURCENK562V_RS34645
NCBI Old Locus Tag BURCENK562V_C0077
RefSeq WP_034178478.1


Feature Type CDS
Coding Frame 1
Product Name
conjugal transfer protein TraH
Evidence for Translation
Charge (pH 7) -4.28
Kyte-Doolittle Hydrophobicity Value -0.187
Molecular Weight (kDa) 52063.7
Isoelectric Point (pI) 5.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG007444 (39 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: ptwH


A Functional oriT in the Ptw Plasmid of Burkholderia cenocepacia Can Be Recognized by the R388 Relaxase TrwC.
Fernández-González E, Bakioui S, Gomes MC, O'Callaghan D, Vergunst AC, Sangari FJ, Llosa M
Front Mol Biosci 2016;3:16
PubMed ID: 27200362
Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538