Burkholderia cenocepacia J2315, BCAM2629 (hmuU)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2629
NCBI Locus Tag	QU43_RS67600
Name	hmuU
Replicon	chromosome 2
Genomic location	2978686 - 2979774 (+ strand)

Cross-References

RefSeq	WP_012493591.1
GI	206564467
Entrez	6930499
GI	206564467
INSDC	CAR56493.1
NCBI Locus Tag	QU43_RS67600
NCBI Old Locus Tag	BCAM2629
RefSeq	WP_012493591.1,GeneID
UniParc	UPI00017BA44C
UniProtKB Acc	B4EKB4
UniProtKB ID	B4EKB4_BURCJ
UniRef100	UniRef100_A0A0D1BPY1
UniRef50	UniRef50_A1UWS5
UniRef90	UniRef90_G7HGP3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative hemin ABC transporter membrane protein
Synonyms
Evidence for Translation
Charge (pH 7)	11.79
Kyte-Doolittle Hydrophobicity Value	0.989
Molecular Weight (kDa)	35993.2
Isoelectric Point (pI)	11.37

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5B58	METAL BINDING PROTEIN	04/25/16	Inward-facing conformation of ABC heme importer BhuUV in complex with periplasmic heme binding protein BhuT from Burkholderia cenocepacia	BURKHOLDERIA CENOCEPACIA J2315	3.21	X-RAY DIFFRACTION	100.0
5B57	METAL TRANSPORT	04/25/16	Inward-facing conformation of ABC heme importer BhuUV from Burkholderia cenocepacia	BURKHOLDERIA CENOCEPACIA J2315	2.8	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004245 (593 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2629 Search term: hmuU Search term: putative hemin ABC transporter membrane protein

Human Homologs

References