Burkholderia cenocepacia J2315, BCAM2468

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2468
NCBI Locus TagQU43_RS66770
Name
Replicon chromosome 2
Genomic location 2792714 - 2794225 (- strand)

Cross-References

RefSeq WP_012493562.1
GI 206564308
Entrez 6930018
GI 206564308
INSDC CAR56333.1
NCBI Locus Tag QU43_RS66770
NCBI Old Locus Tag BCAM2468
RefSeq WP_012493562.1,GeneID
UniParc UPI00017BA365
UniProtKB Acc B4EIN4
UniProtKB ID B4EIN4_BURCJ
UniRef100 UniRef100_U1ZF98
UniRef50 UniRef50_Q9DBF1
UniRef90 UniRef90_A9AMI2

Product

Feature Type CDS
Coding Frame 1
Product Name
putative aldehyde dehydrogenase family protein
Synonyms
Evidence for Translation
Charge (pH 7) -4.99
Kyte-Doolittle Hydrophobicity Value 0.030
Molecular Weight (kDa) 53939.4
Isoelectric Point (pI) 6.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6DBB OXIDOREDUCTASE 05/02/18 Crystal structure of a Putative aldehyde dehydrogenase family protein Burkholderia cenocepacia J2315 in complex with partially reduced NADH BURKHOLDERIA CENOCEPACIA (STRAIN ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 2.1 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004128 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2468

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 7 family member A1 [Source:HGNC Symbol;Acc:HGNC:877]
E-value: 2.1e-123
Percent Identity: 47.3

References

No references are associated with this feature.