Burkholderia cenocepacia J2315, BCAL2844 (ilvE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2844
NCBI Locus TagQU43_RS50835
Name
ilvE
Replicon chromosome 1
Genomic location 3124274 - 3125197 (+ strand)

Cross-References

RefSeq WP_006481735.1
GI 206561181
Entrez 6932834
GI 206561181
INSDC CAR53144.1
NCBI Locus Tag QU43_RS50835
NCBI Old Locus Tag BCAL2844
RefSeq WP_006481735.1,GeneID
UniParc UPI00017B9611
UniProtKB Acc B4EA28
UniProtKB ID B4EA28_BURCJ
UniRef100 UniRef100_A0A095G489
UniRef50 UniRef50_Q2T0T3
UniRef90 UniRef90_Q2T0T3

Product

Feature Type CDS
Coding Frame 1
Product Name
branched-chain amino acid aminotransferase
Synonyms
Evidence for Translation
Charge (pH 7) -2.13
Kyte-Doolittle Hydrophobicity Value -0.164
Molecular Weight (kDa) 33903.2
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3U0G TRANSFERASE 09/28/11 Crystal structure of branched-chain amino acid aminotransferase from burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 1.9 X-RAY DIFFRACTION 93.2
4WHX TRANSFERASE 09/23/14 X-ray Crystal Structure of an Amino Acid Aminotransferase from Burkholderia pseudomallei Bound to the Co-factor Pyridoxal Phosphate BURKHOLDERIA PSEUDOMALLEI 576 2.05 X-RAY DIFFRACTION 93.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002490 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2844
Search term: ilvE

Human Homologs

Ensembl 97, assembly GRCh38.p12
branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]
E-value: 4.4e-15
Percent Identity: 26.9
Ensembl 97, assembly GRCh38.p12
branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]
E-value: 4.4e-15
Percent Identity: 26.9
Ensembl 97, assembly GRCh38.p12
branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]
E-value: 4.4e-15
Percent Identity: 26.9
Ensembl 97, assembly GRCh38.p12
branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]
E-value: 4.4e-15
Percent Identity: 26.9
Ensembl 97, assembly GRCh38.p12
branched chain amino acid transaminase 2 [Source:HGNC Symbol;Acc:HGNC:977]
E-value: 4.4e-15
Percent Identity: 26.9

References

No references are associated with this feature.