Burkholderia cenocepacia J2315, BCAL2181 (pyrG)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2181
NCBI Locus Tag	QU43_RS47515
Name	pyrG
Replicon	chromosome 1
Genomic location	2406009 - 2407667 (- strand)

Cross-References

RefSeq	WP_006478404.1
GI	206560543
Entrez	6932309
GI	206560543
INSDC	CAR52482.1
NCBI Locus Tag	QU43_RS47515
NCBI Old Locus Tag	BCAL2181
RefSeq	WP_006478404.1,GeneID
UniParc	UPI0000E95530
UniProtKB Acc	B4EDA3
UniProtKB ID	PYRG_BURCJ
UniRef100	UniRef100_B1JUY8
UniRef50	UniRef50_P28595
UniRef90	UniRef90_Q13X05

Product

Feature Type	CDS
Coding Frame	1
Product Name	CTP synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-10.54
Kyte-Doolittle Hydrophobicity Value	-0.259
Molecular Weight (kDa)	61206.4
Isoelectric Point (pI)	5.78

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 655 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002002 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2181 Search term: pyrG Search term: CTP synthetase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000352222 CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520] E-value: 2.2e-134 Percent Identity: 45.0
Ensembl 97, assembly GRCh38.p12	ENSP00000401264 CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520] E-value: 2.2e-134 Percent Identity: 45.0
Ensembl 97, assembly GRCh38.p12	ENSP00000369590 CTP synthase 2 [Source:HGNC Symbol;Acc:HGNC:2520] E-value: 2.2e-134 Percent Identity: 45.0

References