Burkholderia cenocepacia J2315, BCAL1951 (glxR)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1951
NCBI Locus Tag	QU43_RS46300
Name	glxR
Replicon	chromosome 1
Genomic location	2150380 - 2151273 (+ strand)

Cross-References

RefSeq	WP_006485940.1
GI	206560315
Entrez	6933742
GI	206560315
INSDC	CAR52252.1
NCBI Locus Tag	QU43_RS46300
NCBI Old Locus Tag	BCAL1951
RefSeq	WP_006485940.1,GeneID
UniParc	UPI00017B925B
UniProtKB Acc	B4EBH9
UniProtKB ID	B4EBH9_BURCJ
UniRef100	UniRef100_B4EBH9
UniRef50	UniRef50_P77161
UniRef90	UniRef90_B4EBH9

Product

Feature Type	CDS
Coding Frame	1
Product Name	2-hydroxy-3-oxopropionate reductase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.17
Kyte-Doolittle Hydrophobicity Value	0.124
Molecular Weight (kDa)	31213.6
Isoelectric Point (pI)	6.72

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 458 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001713 (636 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1951 Search term: glxR Search term: 2-hydroxy-3-oxopropionate reductase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000265395 3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907] E-value: 1.8e-34 Percent Identity: 31.2

References