Strain |
Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest |
Locus Tag |
BTH_II2090
|
NCBI Locus Tag | BTH_RS10690 |
Name |
malC
|
Replicon | chromosome II |
Genomic location | 2554346 - 2555740 (+ strand) |
Transposon Mutants | 2 transposon mutants in E264 ATCC 700388 |
Comment | Belongs to the malleilactone biosynthetic gene cluster |
RefSeq | YP_440278.1 |
GI | 83717350 |
Entrez | 3846721 |
GI | 83717350 |
INSDC | ABC35239.1 |
NCBI Locus Tag | BTH_RS10690 |
NCBI Old Locus Tag | BTH_II2090 |
RefSeq | YP_440278.1 |
UniParc | UPI000066775D |
UniProtKB Acc | Q2T3H1 |
UniProtKB ID | Q2T3H1_BURTA |
UniRef100 | UniRef100_Q2T3H1 |
UniRef50 | UniRef50_Q2T3H1 |
UniRef90 | UniRef90_Q2T3H1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MalC
|
Synonyms |
syringomycin synthesis regulator SyrP |
Evidence for Translation | |
Charge (pH 7) | 24.49 |
Kyte-Doolittle Hydrophobicity Value | -0.622 |
Molecular Weight (kDa) | 52141.3 |
Isoelectric Point (pI) | 10.69 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 71 genera
|
Burkholderia Ortholog Group |
BG019779 (374 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BTH_II2090
Search term: malC
Search term: MalC
|
Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis.
Gupta A, Bedre R, Thapa SS, Sabrin A, Wang G, Dassanayake M, Grove A
ACS Chem Biol 2017 Dec 15;12(12):3012-3021
PubMed ID: 29087175
|
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.
Biggins JB, Ternei MA, Brady SF
J Am Chem Soc 2012 Aug 15;134(32):13192-5
PubMed ID: 22765305
|