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NEWS
June 28, 2010
We experienced an exceptional hardware failure in our database server over the weekend, we moved to a backup system while we replace the failed hardware and have restored full system functional as of mid-day June 29th. We apologize for the inconvenience.
May 13, 2010
Fixed bug on orthologs page which was preventing mouseovers from displaying gene info.
May 3 , 2010
Due to a significant power upgrade affecting the entire Burnaby campus at Simon Fraser University, including all emergency power, www.burkholderia.com will have a scheduled shutdown from Friday, May 14 until Monday May 17th, 2010. We apologize in advance for the inconvenience.
April 20, 2010
New feature for performing comparative analysis of orthologous genes. It can be used for tasks such as 1) finding orthologs present in two or more strains, 2) finding putative core genome for Burkholderia, 3) finding orthologs present in one set of strains that are absent from another set or 4) returning a list of genes from one strain that do not have orthologs in another strain.
An overview of this feature as well as instructions on how to use it is available here.
Genome summary pages now include links for downloading data and more detailed information including links to the NCBI Trace Archive as well as summaries of experiments from EBI ArrayExpress and NCBI Gene Expression Omnibus.
Gene cards now feature tabbed browsing for easier navigation (example).
Fixed bug in gene search that prevented non-coding genes (those without computationally predicted localizations) from being returned.
Updated the list of completed and incomplete genome sequencing projects in the list of Burkholderia genome grojects.
February 9, 2010
Fixed broken GBrowse links that were being generated from GBrowse start page and producing a "500 Internal Server Error".
February 1, 2010
3 new annotation updates.
New feature: DNA motif search tool to allow searching for DNA motifs in all strains available in this database. Results can be downloaded in both comma-separated value and tab-delimited format.
New batch download feature: Ability to download high-precision ortholog predictions from links in genome menu pages (e.g. Orthologs under "Download" tab of J2315 menu) as well as the main downloads page.
New analyses in GBrowse. Computationally-predicted Rho-independent terminators (TransTermHP) and palindromes (EMBOSS). Click here to view an example.
Fixed bug in updates log search that was preventing results from being returned.
Reference sections of gene summary pages now contain full literature citations (previously included just the PMID).
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The aim of this database is to provide a resource for researchers to perform multi-genome comparisons of strains within the Burkholderia cepacia complex and to other Burkholderia genomes. In addition to the publicly available genome annotations downloaded from NCBI, this website provides ortholog and subcellular localization predictions. We welcome input from the Burkholderia research community on how to improve this database and to provide annotation update submissions based on peer-reviewed publications. A better understanding of the factors responsible for virulence in these strains will help researchers identify vaccine targets and drug candidates. | |
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View annotations and analyses for Burkholderia spp. genomes using the Database Search or go directly near the start of each genome (available in 2 formats): |
| Burkholderia ambifaria strain AMMD | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia ambifaria strain MC40-6 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia cenocepacia strain AU 1054 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia cenocepacia strain HI2424 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia cenocepacia strain J2315 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia cenocepacia strain MC0-3 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia lata strain 383 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia mallei strain ATCC 23344 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia mallei strain NCTC 10229 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia mallei strain NCTC 10247 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia mallei strain SAVP1 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia multivorans strain ATCC 17616 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia phymatum strain STM815 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia pseudomallei strain 668 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia pseudomallei strain 1106a | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia pseudomallei strain 1710b | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia pseudomallei strain K96243 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia thailandensis strain E264 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia vietnamiensis strain G4 | [ Gene Card View ] | [ GBrowse View ] |
| Burkholderia xenovorans strain LB400 | [ Gene Card View ] | [ GBrowse View ] |
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We thank Cystic Fibrosis Foundation Therapeutics, Inc (CFFT) for critical funding support for the Burkholderia Genome Database. |