Strain |
Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest |
Locus Tag |
BTH_II2095
|
Name |
malI
|
Replicon | chromosome II |
Genomic location | 2573204 - 2574466 (+ strand) |
Transposon Mutants | 4 transposon mutants in E264 ATCC 700388 |
Comment | Incorrect translation start site called at 2571743 during initial annotation. The site was changed to 2573204 based on alignment with B. pseudomallei K96243 BPSS0303. |
Comment | Belongs to the malleilactone biosynthetic gene cluster |
RefSeq | YP_440283.1 |
GI | 83716834 |
Entrez | 3845242 |
GI | 83716834 |
INSDC | ABC34723.1 |
NCBI Locus Tag | BTH_II2095 |
RefSeq | YP_440283.1 |
UniParc | UPI0000667565 |
UniProtKB Acc | Q2T3G6 |
UniProtKB ID | Q2T3G6_BURTA |
UniRef100 | UniRef100_Q2T3G6 |
UniRef50 | UniRef50_Q2T3G6 |
UniRef90 | UniRef90_Q2T3G6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MalI
|
Synonyms |
diaminopimelate decarboxylase |
Evidence for Translation | |
Charge (pH 7) | -2.17 |
Kyte-Doolittle Hydrophobicity Value | -0.053 |
Molecular Weight (kDa) | 45655.5 |
Isoelectric Point (pI) | 6.69 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 587 genera
|
Burkholderia Ortholog Group |
BG019787 (367 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BTH_II2095
Search term: malI
Search term: MalI
|
Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis.
Gupta A, Bedre R, Thapa SS, Sabrin A, Wang G, Dassanayake M, Grove A
ACS Chem Biol 2017 Dec 15;12(12):3012-3021
PubMed ID: 29087175
|
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.
Biggins JB, Ternei MA, Brady SF
J Am Chem Soc 2012 Aug 15;134(32):13192-5
PubMed ID: 22765305
|