Burkholderia pseudomallei K96243, BPSL1514 (hisS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1514
Name
hisS
Replicon chromosome 1
Genomic location 1752838 - 1754178 (+ strand)

Cross-References

RefSeq YP_108134.1
GI 53719148
Entrez 3092128
GI 53719148
INSDC CAH35515.1
NCBI Locus Tag BPSL1514
RefSeq YP_108134.1,GeneID
UniParc UPI000043B02B
UniProtKB Acc Q63UT2
UniProtKB ID SYH_BURPS
UniRef100 UniRef100_A3NVX0
UniRef50 UniRef50_Q7N705
UniRef90 UniRef90_Q2SWE3

Product

Feature Type CDS
Coding Frame 1
Product Name
histidyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -15.66
Kyte-Doolittle Hydrophobicity Value -0.278
Molecular Weight (kDa) 49628.0
Isoelectric Point (pI) 4.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4E51 LIGASE 03/13/12 Crystal structure of a histidyl-tRNA synthetase HisRS from Burkholderia thailandensis bound to histidine BURKHOLDERIA THAILANDENSIS 2.65 X-RAY DIFFRACTION 96.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001648 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1514
Search term: hisS

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268