Burkholderia cenocepacia J2315, BCAM2701 (acnA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2701
NCBI Locus Tag	QU43_RS67950
Name	acnA
Replicon	chromosome 2
Genomic location	3053567 - 3056161 (- strand)

Cross-References

RefSeq	WP_006481668.1
GI	206564539
Entrez	6930218
GI	206564539
INSDC	CAR56565.1
NCBI Locus Tag	QU43_RS67950
NCBI Old Locus Tag	BCAM2701
RefSeq	WP_006481668.1,GeneID
UniParc	UPI00017BA312
UniProtKB Acc	B4EKX0
UniProtKB ID	B4EKX0_BURCJ
UniRef100	UniRef100_B4EKX0
UniRef50	UniRef50_Q937N8
UniRef90	UniRef90_Q937N8

Product

Feature Type	CDS
Coding Frame	1
Product Name	aconitate hydratase
Synonyms
Evidence for Translation
Charge (pH 7)	-18.81
Kyte-Doolittle Hydrophobicity Value	-0.187
Molecular Weight (kDa)	93866.6
Isoelectric Point (pI)	5.10

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003060 (1309 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2701 Search term: acnA Search term: aconitate hydratase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000438733 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 1.8e-194 Percent Identity: 42.0
Ensembl 97, assembly GRCh38.p12	ENSP00000309477 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 1.8e-194 Percent Identity: 42.0
Ensembl 97, assembly GRCh38.p12	ENSP00000369255 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 1.8e-194 Percent Identity: 42.0

References