Burkholderia cenocepacia J2315, BCAL3256 (mutL)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3256
NCBI Locus Tag	QU43_RS52990
Name	mutL
Replicon	chromosome 1
Genomic location	3562928 - 3564925 (+ strand)

Cross-References

RefSeq	WP_006484994.1
GI	206561596
Entrez	6933105
GI	206561596
INSDC	CAR53580.1
NCBI Locus Tag	QU43_RS52990
NCBI Old Locus Tag	BCAL3256
RefSeq	WP_006484994.1,GeneID
UniParc	UPI00017B999C
UniProtKB Acc	B4EDH2
UniProtKB ID	B4EDH2_BURCJ
UniRef100	UniRef100_B4EDH2
UniRef50	UniRef50_B2JGD0
UniRef90	UniRef90_A4JBT3

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA mismatch repair protein
Synonyms
Evidence for Translation
Charge (pH 7)	-8.35
Kyte-Doolittle Hydrophobicity Value	-0.112
Molecular Weight (kDa)	71114.7
Isoelectric Point (pI)	6.37

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 518 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000642 (574 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3256 Search term: mutL Search term: DNA mismatch repair protein

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000231790 mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127] E-value: 5.7e-44 Percent Identity: 32.9

References