Burkholderia cenocepacia J2315, BCAL1769 (mdlB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1769
NCBI Locus Tag	QU43_RS45385
Name	mdlB
Replicon	chromosome 1
Genomic location	1948577 - 1949743 (+ strand)

Cross-References

RefSeq	YP_002230896.1
GI	206560132
Entrez	6931998
GI	206560132
INSDC	CAR52068.1
NCBI Locus Tag	QU43_RS45385
NCBI Old Locus Tag	BCAL1769
RefSeq	YP_002230896.1
UniParc	UPI00017B93D9
UniProtKB Acc	B4E9V0
UniProtKB ID	B4E9V0_BURCJ
UniRef100	UniRef100_B4E9V0
UniRef50	UniRef50_B4E9V0
UniRef90	UniRef90_B4E9V0

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative L(+)-mandelate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	11.89
Kyte-Doolittle Hydrophobicity Value	-0.001
Molecular Weight (kDa)	42165.9
Isoelectric Point (pI)	10.53

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543 Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 289 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG006100 (916 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1769 Search term: mdlB Search term: putative L(+)-mandelate dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000483507 hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] E-value: 3.5e-49 Percent Identity: 33.9
Ensembl 97, assembly GRCh38.p12	ENSP00000354314 hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] E-value: 3.5e-49 Percent Identity: 33.9
Ensembl 97, assembly GRCh38.p12	ENSP00000316339 hydroxyacid oxidase 2 [Source:HGNC Symbol;Acc:HGNC:4810] E-value: 3.5e-49 Percent Identity: 33.9

References