Burkholderia cenocepacia J2315, BCAL1769 (mdlB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000138
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000138
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000138
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00620 Pyruvate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd02809 alpha_hydroxyacid_oxid_FMN IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent 9 376 4.39784E-125
Pfam PF01070 FMN-dependent dehydrogenase IPR000262 FMN-dependent dehydrogenase 15 379 1.1E-119
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 4 386 2.7E-117
SUPERFAMILY SSF51395 4 379 2.63E-88
PIRSF PIRSF000138 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent 1 383 2.0E-128
ProSiteProfiles PS51349 FMN-dependent alpha-hydroxy acid dehydrogenase domain profile. IPR037396 FMN hydroxy acid dehydrogenase domain 1 384 93.434
ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site 277 283 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.