Burkholderia cenocepacia J2315, BCAM2738 (ispH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051745 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00216
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00216
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0050992 dimethylallyl diphosphate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00216
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00216
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc methylerythritol phosphate pathway II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00900 Terpenoid backbone biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj00900 Terpenoid backbone biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1 283 37.378
Gene3D G3DSA:3.40.1010.20 6 279 5.1E-108
Gene3D G3DSA:3.40.50.11270 12 96 5.1E-108
Pfam PF02401 LytB protein IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 279 2.3E-90
CDD cd13944 lytB_ispH IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 279 4.11716E-143
TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 281 4.0E-98
Gene3D G3DSA:3.40.1010.20 97 193 5.1E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.