Burkholderia cenocepacia J2315, BCAM2703 (prpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0046421 methylisocitrate lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01939
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019629 propionate catabolic process, 2-methylcitrate cycle
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01939
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00640 Propanoate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 2-methylcitrate cycle II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00640 Propanoate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00377 ICL_PEPM IPR039556 ICL/PEPM domain 41 283 5.0931E-97
Hamap MF_01939 2-methylisocitrate lyase [prpB]. IPR012695 2-methylisocitrate lyase 33 323 51.941
Gene3D G3DSA:3.20.20.60 IPR040442 Pyruvate kinase-like domain superfamily 29 325 4.9E-109
SUPERFAMILY SSF51621 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily 27 318 1.39E-101
TIGRFAM TIGR02317 prpB: methylisocitrate lyase IPR012695 2-methylisocitrate lyase 38 321 3.0E-128
Pfam PF13714 Phosphoenolpyruvate phosphomutase 42 282 1.7E-50
ProSitePatterns PS00161 Isocitrate lyase signature. IPR018523 Isocitrate lyase/phosphorylmutase, conserved site 151 156 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.