Burkholderia cenocepacia J2315, BCAM2343 (betA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019285 glycine betaine biosynthetic process from choline
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008812 choline dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008812 choline dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019285 glycine betaine biosynthetic process from choline
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01810
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000137
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00260 Glycine, serine and threonine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc choline degradation IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc glycine betaine biosynthesis II (Gram-positive bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS00623 GMC oxidoreductases signature 1. IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal 85 108 -
TIGRFAM TIGR01810 betA: choline dehydrogenase IPR011533 Oxygen-dependent choline dehydrogenase 7 538 8.6E-280
Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. IPR011533 Oxygen-dependent choline dehydrogenase 4 555 60.4
SUPERFAMILY SSF54373 296 478 1.47E-61
Gene3D G3DSA:4.10.450.10 IPR027424 Glucose Oxidase, domain 2 39 202 4.8E-175
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 5 532 4.8E-175
Gene3D G3DSA:3.30.410.40 155 475 4.8E-175
PIRSF PIRSF000137 IPR012132 Glucose-methanol-choline oxidoreductase 1 542 8.0E-142
Pfam PF00732 GMC oxidoreductase IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal 6 301 1.7E-99
Pfam PF05199 GMC oxidoreductase IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal 394 528 1.6E-38
Gene3D G3DSA:1.10.1220.110 100 154 4.8E-175
SUPERFAMILY SSF51905 IPR036188 FAD/NAD(P)-binding domain superfamily 1 536 1.44E-89
ProSitePatterns PS00624 GMC oxidoreductases signature 2. IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal 260 274 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.