Burkholderia cenocepacia J2315, BCAM1417

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016021 integral component of membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj02020 Two-component system 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 235 301 1.5E-13
ProSiteProfiles PS50885 HAMP domain profile. IPR003660 HAMP domain 180 233 8.782
CDD cd06225 HAMP IPR003660 HAMP domain 183 230 0.00209722
SMART SM00304 IPR003660 HAMP domain 180 233 6.1E-6
SUPERFAMILY SSF47384 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 217 301 5.3E-16
MobiDBLite mobidb-lite consensus disorder prediction 467 494 -
Pfam PF00672 HAMP domain IPR003660 HAMP domain 178 230 1.0E-6
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 399 409 2.1E-5
CDD cd00075 HATPase 349 446 1.01483E-23
ProSiteProfiles PS51257 Prokaryotic membrane lipoprotein lipid attachment site profile. 1 26 6.0
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 344 455 1.7E-22
SMART SM00388 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 234 301 1.2E-15
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 290 445 1.7E-28
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 345 439 9.8E-14
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 307 454 2.4E-24
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 416 434 2.1E-5
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 241 455 33.338
Gene3D G3DSA:1.10.287.130 184 302 1.7E-20
TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase IPR006290 Heavy metal sensor kinase 3 451 1.7E-112
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 233 297 3.59512E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.