Burkholderia cenocepacia J2315, BCAM0817

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0030976	thiamine pyrophosphate binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02776	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02775	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000287	magnesium ion binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PS00187	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00660	C5-Branched dibasic acid metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01230	Biosynthesis of amino acids	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00770	Pantothenate and CoA biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01210	2-Oxocarboxylic acid metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00290	Valine, leucine and isoleucine biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00650	Butanoate metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	IPR011766	Thiamine pyrophosphate enzyme, C-terminal TPP-binding	378	524	8.8E-40
Coils	Coil				532	546	-
Pfam	PF00205	Thiamine pyrophosphate enzyme, central domain	IPR012000	Thiamine pyrophosphate enzyme, central domain	186	318	1.8E-31
SUPERFAMILY	SSF52467		IPR029035	DHS-like NAD/FAD-binding domain superfamily	153	344	8.8E-41
SUPERFAMILY	SSF52518		IPR029061	Thiamin diphosphate-binding fold	1	177	5.05E-50
CDD	cd02010	TPP_ALS			358	534	2.3408E-108
Gene3D	G3DSA:3.40.50.1220				178	328	3.1E-37
Pfam	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	IPR012001	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	1	167	5.8E-55
MobiDBLite	mobidb-lite	consensus disorder prediction			149	173	-
Gene3D	G3DSA:3.40.50.970				1	173	1.2E-59
Gene3D	G3DSA:3.40.50.970				337	539	7.6E-55
SUPERFAMILY	SSF52518		IPR029061	Thiamin diphosphate-binding fold	355	539	2.32E-58
ProSitePatterns	PS00187	Thiamine pyrophosphate enzymes signature.	IPR000399	TPP-binding enzyme, conserved site	415	434	-
CDD	cd07035	TPP_PYR_POX_like			5	159	4.43942E-64

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.