Burkholderia cenocepacia J2315, BCAL2389 (purD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004637 phosphoribosylamine-glycine ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02843
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009113 purine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02843
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc 5-aminoimidazole ribonucleotide biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 5-aminoimidazole ribonucleotide biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00230 Purine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc superpathway of 5-aminoimidazole ribonucleotide biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM01209 101 294 3.5E-138
Gene3D G3DSA:3.30.1490.20 IPR013815 ATP-grasp fold, subdomain 1 119 188 1.2E-27
SUPERFAMILY SSF52440 IPR016185 Pre-ATP-grasp domain superfamily 1 101 1.44E-34
Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain IPR020562 Phosphoribosylglycinamide synthetase, N-terminal 1 100 1.5E-34
SUPERFAMILY SSF56059 102 324 1.34E-64
Gene3D G3DSA:3.40.50.20 1 93 5.4E-35
Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain IPR020560 Phosphoribosylglycinamide synthetase, C-domain 329 419 2.6E-30
SMART SM01210 IPR020560 Phosphoribosylglycinamide synthetase, C-domain 328 421 2.4E-52
Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. IPR000115 Phosphoribosylglycinamide synthetase 1 421 43.217
ProSiteProfiles PS50975 ATP-grasp fold profile. IPR011761 ATP-grasp fold 107 314 42.415
SUPERFAMILY SSF51246 IPR011054 Rudiment single hybrid motif 327 421 6.43E-32
Gene3D G3DSA:3.30.470.20 189 327 7.2E-57
Gene3D G3DSA:3.90.600.10 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily 328 426 6.0E-34
TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase IPR000115 Phosphoribosylglycinamide synthetase 1 421 4.1E-174
Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 294 9.7E-78

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.