Burkholderia cenocepacia J2315, BCAL1104 (thiC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016830 carbon-carbon lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00089
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00190
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009228 thiamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00190
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00730 Thiamine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00730 Thiamine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SFLD SFLDS00113 Radical SAM Phosphomethylpyrimidine Synthase 11 642 0.0
TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B 138 607 1.2E-216
SFLD SFLDG01114 phosphomethylpyrimidine synthase (ThiC) 17 641 0.0
Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. IPR037509 Phosphomethylpyrimidine synthase 138 609 100.074
Pfam PF13667 ThiC-associated domain IPR025747 ThiC-associated domain 21 98 2.1E-34
Coils Coil 642 643 -
Gene3D G3DSA:3.20.20.540 IPR038521 ThiC/Bza superfamily 227 540 3.3E-153
SFLD SFLDF00407 phosphomethylpyrimidine synthase (ThiC) IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B 139 604 0.0
Pfam PF01964 Radical SAM ThiC family IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B 139 604 2.7E-200

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.