Burkholderia cenocepacia J2315, BCAL0479 (mrdA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj01501 beta-Lactam resistance 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00550 Peptidoglycan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00550 Peptidoglycan biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc peptidoglycan biosynthesis II (staphylococci) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc peptidoglycan biosynthesis IV (Enterococcus faecium) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.1390.30 82 158 8.4E-41
TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 IPR017790 Penicillin-binding protein 2 17 627 1.3E-231
SUPERFAMILY SSF56601 IPR012338 Beta-lactamase/transpeptidase-like 266 627 5.05E-102
Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. IPR017790 Penicillin-binding protein 2 3 631 49.958
SUPERFAMILY SSF56519 IPR036138 Penicillin-binding protein, dimerisation domain superfamily 53 265 4.05E-46
Gene3D G3DSA:3.90.1310.10 61 260 8.4E-41
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 283 624 2.1E-69
MobiDBLite mobidb-lite consensus disorder prediction 676 710 -
Pfam PF03717 Penicillin-binding Protein dimerisation domain IPR005311 Penicillin-binding protein, dimerisation domain 61 251 3.0E-40
Gene3D G3DSA:3.40.710.10 261 638 1.5E-101
MobiDBLite mobidb-lite consensus disorder prediction 190 210 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.