Burkholderia cenocepacia J2315, BCAL0421 (gyrB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00433	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00433	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00433	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0005694	chromosome	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01898	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006265	DNA topological change	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00433	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
CDD	cd00822	TopoII_Trans_DNA_gyrase			244	401	3.6507E-79
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	398	418	6.6E-72
PRINTS	PR00418	DNA topoisomerase II family signature			444	458	1.4E-67
Pfam	PF00986	DNA gyrase B subunit, carboxyl terminus	IPR002288	DNA gyrase B subunit, C-terminal	752	813	2.5E-29
Pfam	PF00204	DNA gyrase B	IPR013506	DNA topoisomerase, type IIA, subunit B, domain 2	245	414	2.6E-57
PRINTS	PR00418	DNA topoisomerase II family signature			79	92	1.4E-67
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	41	198	6.6E-20
PRINTS	PR00418	DNA topoisomerase II family signature			292	305	1.4E-67
Gene3D	G3DSA:3.30.565.10		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	11	244	5.5E-89
PRINTS	PR00418	DNA topoisomerase II family signature			529	546	1.4E-67
Gene3D	G3DSA:3.30.230.10		IPR014721	Ribosomal protein S5 domain 2-type fold, subgroup	245	416	3.6E-72
PRINTS	PR00418	DNA topoisomerase II family signature			756	772	1.4E-67
SUPERFAMILY	SSF55874		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	14	240	2.49E-65
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	384	398	6.6E-72
Pfam	PF18053	DNA gyrase B subunit insert domain	IPR041423	DNA gyrase subunit B insert domain	589	750	1.5E-50
ProSitePatterns	PS00177	DNA topoisomerase II signature.	IPR018522	DNA topoisomerase, type IIA, conserved site	446	454	-
Gene3D	G3DSA:3.40.50.670		IPR013759	DNA topoisomerase, type IIA, subunit B, C-terminal	722	822	1.2E-24
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	777	789	6.6E-72
PRINTS	PR00418	DNA topoisomerase II family signature			511	527	1.4E-67
Hamap	MF_01898	DNA gyrase subunit B [gyrB].	IPR011557	DNA gyrase, subunit B	11	824	99.229
SUPERFAMILY	SSF56719		IPR013760	DNA topoisomerase, type IIA-like domain superfamily	418	814	1.88E-86
CDD	cd03366	TOPRIM_TopoIIA_GyrB	IPR034160	DNA gyrase subunit B, TOPRIM domain	442	556	2.91827E-78
Pfam	PF01751	Toprim domain	IPR006171	TOPRIM domain	443	554	3.3E-17
PRINTS	PR00418	DNA topoisomerase II family signature			549	561	1.4E-67
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	336	352	6.6E-72
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	220	233	6.6E-72
SUPERFAMILY	SSF54211		IPR020568	Ribosomal protein S5 domain 2-type fold	245	416	1.19E-57
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	14	24	6.6E-72
TIGRFAM	TIGR01059	gyrB: DNA gyrase, B subunit	IPR011557	DNA gyrase, subunit B	14	824	2.1E-292
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	494	503	6.6E-72
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	244	266	6.6E-72
ProSiteProfiles	PS50880	Toprim domain profile.	IPR006171	TOPRIM domain	442	557	21.192
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	793	809	6.6E-72
Gene3D	G3DSA:3.40.50.670		IPR013759	DNA topoisomerase, type IIA, subunit B, C-terminal	422	592	1.4E-73
SMART	SM00433		IPR001241	DNA topoisomerase, type IIA	44	817	3.6E-251
SMART	SM00387		IPR003594	Histidine kinase/HSP90-like ATPase	40	200	4.6E-21
CDD	cd16928	HATPase_GyrB-like			45	240	1.03312E-99
PRINTS	PR01159	DNA gyrase subunit B signature	IPR000565	DNA topoisomerase, type IIA, subunit B	205	220	6.6E-72
PRINTS	PR00418	DNA topoisomerase II family signature			44	59	1.4E-67
PRINTS	PR00418	DNA topoisomerase II family signature			126	140	1.4E-67

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.