Burkholderia cenocepacia J2315, BCAL0300 (thiE)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003824 | catalytic activity |
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009228 | thiamine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00097
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004789 | thiamine-phosphate diphosphorylase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00097
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | thiamine diphosphate biosynthesis II (Bacillus) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00730 | Thiamine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00730 | Thiamine metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | thiamine diphosphate biosynthesis IV (eukaryotes) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | thiamine diphosphate biosynthesis III (Staphylococcus) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | thiamine salvage IV (yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | thiamine diphosphate biosynthesis I (E. coli) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | thiamine salvage II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | thiamine formation from pyrithiamine and oxythiamine (yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.20.20.70 | IPR013785 | Aldolase-type TIM barrel | 168 | 369 | 4.1E-52 | |
| TIGRFAM | TIGR00693 | thiE: thiamine-phosphate diphosphorylase | IPR034291 | Thiamine phosphate synthase | 181 | 360 | 7.4E-44 |
| CDD | cd00564 | TMP_TenI | IPR022998 | Thiamine phosphate synthase/TenI | 174 | 339 | 7.16797E-50 |
| Hamap | MF_00097 | Thiamine-phosphate synthase [thiE]. | IPR034291 | Thiamine phosphate synthase | 169 | 368 | 19.202 |
| Pfam | PF02581 | Thiamine monophosphate synthase | IPR022998 | Thiamine phosphate synthase/TenI | 180 | 350 | 5.9E-49 |
| SUPERFAMILY | SSF51391 | IPR036206 | Thiamin phosphate synthase superfamily | 165 | 365 | 1.15E-56 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.