Burkholderia thailandensis E264 ATCC 700388, BTH_I1469 (rmlB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009225 nucleotide-sugar metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01181
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008460 dTDP-glucose 4,6-dehydratase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01181
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc dTDP-L-megosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-α-D-mycaminose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-D-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-β-L-digitoxose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-desosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-<i>N</i>-acetylviosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-daunosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-&beta;-L-4-<i>epi</i>-vancosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-<i>N</i>-acetylthomosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00523 Polyketide sugar unit biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00525 Acarbose and validamycin biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte00523 Polyketide sugar unit biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00521 Streptomycin biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-4-<i>O</i>-demethyl-&beta;-L-noviose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-3-acetamido-3,6-dideoxy-&alpha;-D-glucose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-3-acetamido-&alpha;-D-fucose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-mycarose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-forosamine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte00521 Streptomycin biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc dTDP-6-deoxy-&alpha;-D-allose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-L-olivose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc dTDP-D-&beta;-fucofuranose biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 42 391 1.1E-88
Pfam PF16363 GDP-mannose 4,6 dehydratase IPR016040 NAD(P)-binding domain 47 366 5.6E-100
CDD cd05246 dTDP_GD_SDR_e IPR005888 dTDP-glucose 4,6-dehydratase 46 375 0.0
Gene3D G3DSA:3.90.25.10 244 372 2.8E-129
TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase IPR005888 dTDP-glucose 4,6-dehydratase 46 379 2.9E-151
Gene3D G3DSA:3.40.50.720 46 365 2.8E-129

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.