Burkholderia thailandensis E264 ATCC 700388, BTH_II1234 (btaL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0017000	antibiotic biosynthetic process	IGC Inferred from Genomic Context	ECO:0000317 genomic context evidence used in manual assertion	20095633	Reviewed by curator
Molecular Function	GO:0031177	phosphopantetheine binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00823	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.40.47.10	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016740	transferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.40.366.10	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:3.40.50.1820		IPR029058	Alpha/Beta hydrolase fold	1395	1502	8.1E-24
ProSitePatterns	PS00012	Phosphopantetheine attachment site.	IPR006162	Phosphopantetheine attachment site	1428	1443	-
SUPERFAMILY	SSF51735		IPR036291	NAD(P)-binding domain superfamily	1119	1361	2.8E-24
Pfam	PF16197	Ketoacyl-synthetase C-terminal extension	IPR032821	Ketoacyl-synthetase, C-terminal extension	376	461	8.2E-9
SMART	SM00827	Acyl transferase domain in polyketide synthase (PKS) enzymes.	IPR020801	Polyketide synthase, acyl transferase domain	511	801	6.9E-69
Gene3D	G3DSA:3.30.70.3290				439	847	6.1E-95
SMART	SM00822	This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.			1120	1318	1.3E-9
SMART	SM00825	Beta-ketoacyl synthase	IPR020841	Polyketide synthase, beta-ketoacyl synthase domain	4	426	3.1E-138
Gene3D	G3DSA:3.40.47.10		IPR016039	Thiolase-like	1	438	1.7E-143
ProSitePatterns	PS00606	Beta-ketoacyl synthases active site.	IPR018201	Beta-ketoacyl synthase, active site	159	175	-
Pfam	PF02801	Beta-ketoacyl synthase, C-terminal domain	IPR014031	Beta-ketoacyl synthase, C-terminal	255	372	4.1E-38
MobiDBLite	mobidb-lite	consensus disorder prediction			1497	1524	-
CDD	cd00833	PKS			2	421	5.14425E-165
SUPERFAMILY	SSF55048		IPR016036	Malonyl-CoA ACP transacylase, ACP-binding	632	692	7.06E-8
Pfam	PF08659	KR domain	IPR013968	Polyketide synthase, ketoreductase domain	1122	1316	3.7E-23
Pfam	PF00109	Beta-ketoacyl synthase, N-terminal domain	IPR014030	Beta-ketoacyl synthase, N-terminal	1	246	3.8E-51
Pfam	PF00550	Phosphopantetheine attachment site	IPR009081	Phosphopantetheine binding ACP domain	1406	1467	6.7E-12
SUPERFAMILY	SSF52151		IPR016035	Acyl transferase/acyl hydrolase/lysophospholipase	509	785	1.07E-53
SUPERFAMILY	SSF53901		IPR016039	Thiolase-like	2	421	4.06E-71
Gene3D	G3DSA:3.40.50.720				849	1385	7.2E-55
SUPERFAMILY	SSF47336		IPR036736	ACP-like superfamily	1397	1467	1.83E-18
Pfam	PF00698	Acyl transferase domain	IPR014043	Acyl transferase	511	761	5.8E-40
SMART	SM00823	Phosphopantetheine attachment site	IPR020806	Polyketide synthase, phosphopantetheine-binding domain	1404	1473	0.0048
ProSiteProfiles	PS50075	Carrier protein (CP) domain profile.	IPR009081	Phosphopantetheine binding ACP domain	1398	1473	16.563
Gene3D	G3DSA:3.40.366.10		IPR001227	Acyl transferase domain superfamily	509	803	6.1E-95

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.