Burkholderia pseudomallei K96243, BPSL2992

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01183
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00317
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01183
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00230 Purine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00480 Glutathione metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides biosynthesis from CTP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00983 Drug metabolism - other enzymes InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 691 714 4.0E-44
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 583 594 4.0E-44
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 448 467 4.0E-44
SUPERFAMILY SSF48168 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal 160 371 3.79E-63
CDD cd01679 RNR_I 321 915 0.0
ProSiteProfiles PS51161 ATP-cone domain profile. IPR005144 ATP-cone domain 155 244 14.329
ProSiteProfiles PS51161 ATP-cone domain profile. IPR005144 ATP-cone domain 38 138 19.403
ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. IPR000788 Ribonucleotide reductase large subunit, C-terminal 756 778 -
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 663 685 4.0E-44
Pfam PF00317 Ribonucleotide reductase, all-alpha domain IPR013509 Ribonucleotide reductase large subunit, N-terminal 296 369 2.5E-22
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 625 648 4.0E-44
Pfam PF03477 ATP cone domain IPR005144 ATP-cone domain 39 135 2.5E-18
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 373 912 4.1E-181
TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit IPR013346 Ribonucleotide reductase, class I , alpha subunit 299 915 3.5E-211
Gene3D G3DSA:3.20.70.20 226 923 6.3E-246
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 767 794 4.0E-44
SUPERFAMILY SSF51998 372 915 1.74E-179

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.