Burkholderia pseudomallei K96243, BPSL2009 (alaS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006419 alanyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF101353
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50860
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF101353
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004813 alanine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF101353
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00863
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF101353
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00863
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00863
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00036_B Alanine--tRNA ligase [alaS]. IPR023033 Alanine-tRNA ligase, eukaryota/bacteria 1 874 205.767
SUPERFAMILY SSF101353 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily 252 444 4.71E-61
Coils Coil 874 874 -
SUPERFAMILY SSF55186 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily 552 707 5.89E-49
Pfam PF01411 tRNA synthetases class II (A) IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal 5 555 3.3E-223
Gene3D G3DSA:3.10.310.40 763 871 1.0E-32
ProSiteProfiles PS50860 Alanyl-transfer RNA synthetases family profile. IPR018165 Alanyl-tRNA synthetase, class IIc, core domain 1 708 130.968
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 74 85 1.9E-32
Pfam PF02272 DHHA1 domain IPR003156 DHHA1 domain 733 870 1.6E-27
Gene3D G3DSA:3.30.54.20 624 676 2.7E-48
Coils Coil 731 758 -
SUPERFAMILY SSF55681 2 251 2.16E-109
Coils Coil 782 802 -
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 302 315 1.9E-32
Gene3D G3DSA:2.40.30.130 453 552 1.7E-10
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 278 294 1.9E-32
SMART SM00863 IPR012947 Threonyl/alanyl tRNA synthetase, SAD 653 695 3.1E-18
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 205 216 1.9E-32
PRINTS PR00980 Alanyl-tRNA synthetase signature IPR002318 Alanine-tRNA ligase, class IIc 232 245 1.9E-32
Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain IPR012947 Threonyl/alanyl tRNA synthetase, SAD 653 695 3.8E-15
Gene3D G3DSA:3.30.930.10 1 248 2.7E-119
CDD cd00673 AlaRS_core 3 247 5.69096E-140
SUPERFAMILY SSF50447 IPR009000 Translation protein, beta-barrel domain superfamily 453 552 1.14E-18
Gene3D G3DSA:3.30.980.10 562 696 2.7E-48
TIGRFAM TIGR00344 alaS: alanine--tRNA ligase IPR002318 Alanine-tRNA ligase, class IIc 5 853 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.