Burkholderia pseudomallei K96243, BPSL1524 (purA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004019 adenylosuccinate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00788
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005525 GTP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00788
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006164 purine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00788
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00230 Purine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00250 Alanine, aspartate and glutamate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc adenosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00709 Adenylosuccinate synthetase IPR001114 Adenylosuccinate synthetase 14 440 9.3E-175
ProSitePatterns PS00513 Adenylosuccinate synthetase active site. IPR033128 Adenylosuccinate synthase, active site 142 153 -
Gene3D G3DSA:1.10.300.10 IPR042110 Adenylosuccinate synthetase, domain 2 111 210 2.2E-103
Gene3D G3DSA:3.40.440.10 IPR042109 Adenylosuccinate synthetase, domain 1 15 264 2.2E-103
SUPERFAMILY SSF52540 IPR027417 P-loop containing nucleoside triphosphate hydrolase 13 446 2.55E-169
Gene3D G3DSA:3.90.170.10 IPR042111 Adenylosuccinate synthetase, domain 3 276 448 2.0E-71
TIGRFAM TIGR00184 purA: adenylosuccinate synthase IPR001114 Adenylosuccinate synthetase 15 446 1.4E-172
Hamap MF_00011 Adenylosuccinate synthetase [purA]. IPR001114 Adenylosuccinate synthetase 1 448 210.607
SMART SM00788 IPR001114 Adenylosuccinate synthetase 13 441 3.3E-288
CDD cd03108 AdSS IPR001114 Adenylosuccinate synthetase 12 441 1.25757E-160
ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. IPR018220 Adenylosuccinate synthase, GTP-binding site 20 27 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.