Burkholderia pseudomallei K96243, BPSL1477 (hom)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00742
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004412 homoserine dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000098
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03447
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006520 cellular amino acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00742
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03447
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00260 Glycine, serine and threonine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00300 Lysine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00270 Cysteine and methionine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00300 Lysine biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS01042 Homoserine dehydrogenase signature. IPR019811 Homoserine dehydrogenase, conserved site 186 208 -
PIRSF PIRSF000098 IPR016204 Homoserine dehydrogenase 1 441 8.9E-165
SUPERFAMILY SSF55021 355 430 5.66E-11
Gene3D G3DSA:3.40.50.720 4 343 9.0E-167
Gene3D G3DSA:3.30.70.260 352 429 9.0E-167
SUPERFAMILY SSF55347 140 305 6.47E-53
Pfam PF01842 ACT domain IPR002912 ACT domain 357 423 1.4E-12
CDD cd04881 ACT_HSDH-Hom 357 439 4.60463E-27
ProSiteProfiles PS51671 ACT domain profile. IPR002912 ACT domain 358 438 14.371
Pfam PF03447 Homoserine dehydrogenase, NAD binding domain IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding 10 132 1.1E-18
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 1 161 8.71E-33
Gene3D G3DSA:3.30.360.10 139 351 9.0E-167
Pfam PF00742 Homoserine dehydrogenase IPR001342 Homoserine dehydrogenase, catalytic 140 318 4.1E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.