Burkholderia cenocepacia AU 1054, BCEN_RS12435

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03717
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00550 Peptidoglycan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc peptidoglycan biosynthesis II (staphylococci) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc peptidoglycan biosynthesis IV (Enterococcus faecium) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
MobiDBLite mobidb-lite consensus disorder prediction 190 210 -
Pfam PF03717 Penicillin-binding Protein dimerisation domain IPR005311 Penicillin-binding protein, dimerisation domain 61 251 5.4E-40
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 283 624 2.0E-69
MobiDBLite mobidb-lite consensus disorder prediction 715 765 -
Gene3D G3DSA:3.40.710.10 261 638 2.0E-101
TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 IPR017790 Penicillin-binding protein 2 17 627 3.1E-231
Gene3D G3DSA:3.90.1310.10 61 260 1.1E-40
Gene3D G3DSA:3.30.1390.30 82 158 1.1E-40
SUPERFAMILY SSF56519 IPR036138 Penicillin-binding protein, dimerisation domain superfamily 53 265 6.8E-46
SUPERFAMILY SSF56601 IPR012338 Beta-lactamase/transpeptidase-like 266 627 1.07E-101
Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. IPR017790 Penicillin-binding protein 2 3 631 49.931

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.