Burkholderia cenocepacia AU 1054, BCEN_RS10785 (purU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016742 hydroxymethyl-, formyl- and related transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006189 'de novo' IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00655
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008864 formyltetrahydrofolate deformylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00655
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc formaldehyde oxidation VII (THF pathway) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc purine nucleobases degradation II (anaerobic) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00670 One carbon pool by folate InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc folate transformations I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00630 Glyoxylate and dicarboxylate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. IPR004810 Formyltetrahydrofolate deformylase 4 293 48.098
PIRSF PIRSF036480 4 294 9.5E-111
ProSiteProfiles PS51671 ACT domain profile. IPR002912 ACT domain 8 99 8.849
SUPERFAMILY SSF53328 IPR036477 Formyl transferase, N-terminal domain superfamily 95 294 3.92E-63
SUPERFAMILY SSF55021 6 92 6.25E-16
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 41 53 8.4E-53
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 267 292 8.4E-53
CDD cd08648 FMT_core_Formyl-FH4-Hydrolase_C IPR041729 Formyltetrahydrofolate deformylase, C-terminal hydrolase domain 94 293 4.62405E-122
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 245 267 8.4E-53
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 95 117 8.4E-53
Pfam PF00551 Formyl transferase IPR002376 Formyl transferase, N-terminal 95 274 2.3E-37
Gene3D G3DSA:3.40.50.170 94 293 3.0E-72
CDD cd04875 ACT_F4HF-DF 8 85 7.14551E-30
TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase IPR004810 Formyltetrahydrofolate deformylase 8 293 1.6E-101
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 9 35 8.4E-53
Gene3D G3DSA:3.30.70.260 3 92 4.7E-28
PRINTS PR01575 Formyltetrahydrofolate deformylase signature IPR004810 Formyltetrahydrofolate deformylase 117 144 8.4E-53

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.