Burkholderia cenocepacia AU 1054, BCEN_RS04640

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019310 inositol catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR04377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR04377
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00562 Inositol phosphate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 226 357 2.8E-35
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 403 612 1.24E-45
SUPERFAMILY SSF52467 IPR029035 DHS-like NAD/FAD-binding domain superfamily 187 386 5.01E-43
TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase 6 626 8.9E-261
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 2 216 8.16E-33
ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. IPR000399 TPP-binding enzyme, conserved site 464 483 -
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 8 205 4.5E-49
Gene3D G3DSA:3.40.50.1220 217 406 1.8E-37
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding 428 582 5.3E-35
Gene3D G3DSA:3.40.50.970 407 593 1.6E-39
CDD cd07035 TPP_PYR_POX_like 40 194 2.24389E-12
Gene3D G3DSA:3.40.50.970 5 206 1.5E-30

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.